Blue Kollagen. Is a nutraceutical composed of Marine hydrolyzed collagen 10 g (10% minimum hydroxyproline), Low molecular weight hyaluronic acid of vegetable origin, cysteine 250 mg, Lithotamnium calcareum red alga thallus extract (7% silica), vitamin C, resveratrol, astaxanthin, biotin, zinc, lycopene, L-cysteine. Useful in all cases of reduced dietary intake or increased need for useful components to improve collagen synthesis in the body and with anti-aging properties.
Blue Kollagen Is an all-in one formula designed to favor the synthesis of collagen and with powerful anti-aging components to improve skin, hair, nails, support, reduce fine lines & wrinkles to look and feel younger.
COLLAGEN SYNTHESIS COMPLEX
(Marine Collagen & Hyaluronic Acid, Vitamin C, Silicon and Resveratrol)
Collagen is one of the most important proteins in vertebrates and represents one third of the total proteins of the human body, where it plays a fundamental role in the structure and functionality of organs and tissues, such as skin, cartilage, muscle tissue. It has been established that the collagen fibers are damaged over time: at the age of 25 cells begin to lose the ability to synthesize collagen, whose production decreases by 1.5% per year. This process is accentuated over 45 years old and when approaching 60, the production of collagen has decreased by over 35%, losing thickness and strength. Collagen holds all the living tissues together and ensures the integrity, elasticity, regeneration of the skin, cartilages and bones and maintenance of tonicity of the skin thanks to the serum proteins, the hydroxyproline, cystine and silicon amino acids. Collagen accounts for 80% of our connective tissues and 30% of proteins in our body.
Marine Collagen & Hyaluronic Acid: Thanks to the synergy of marine collagen and hyaluronic acid, Blue Kollagen helps in the recovery and regeneration process of skin cells and connective tissue of the face and of the whole body. It visibly reduces the appearance of aged skin which is deeply nourished and vitality restored. The brightness of the skin increases, as does the health of the nails. The product makes the skin more turgid and regains its youthful appearance.
Marine collagen is a pure form of hypoallergenic protein produced from the skins of fish. Fish skins remaining from food production are thoroughly washed, then hydrolyzed by an acid and a food grade enzyme to yield marine collagen peptides, which have a low molecular weight for easy digestion and absorption. Marine collagen differs from bovine or porcine-derived collagen in that it contains higher amounts of the amino acids glycine and proline, which have been particularly associated with promoting healthy hair, skin and nails1-4.
Vitamin C: (ascorbic acid) is a cofactor for several enzymes, most notably proline hydroxylase, that are required for collagen synthesis. It cannot be made by the body, and must be obtained from the diet. It is essential for the formation of collagen, it helps to maintain the integrity of substances of mesenchymal origin (connective tissue, osteoid tissue and dentin). In the absence of vitamin C, cells cannot hydrogenate proline in -y positions, resulting in an instability of the collagen. Blue Kollagen contains natural vitamin C extracted from Malpighia glabra, a plant that grows in Central and South America. The fruit of the acerola cherry is rich in natural vitamin C. without chemical ingredients and without the addition of artificial vitamin, which therefore provides a vitamin C that is better recognized and better assimilated by the body. The acerola fruits favor the body’s natural defenses, have a supporting and restorative action and have an antioxidant effect5.
Lithothamnium calcareum. Silicon is a structural element of connective tissue and enters the constitution of the main macromolecules such as elastin, collagen, proteoglycans and glycoproteins, promoting their regeneration. Collagen synthesis is silicon-dependent, which influences the hydroxylation process of proline in hydroxyproline. The silicon content is closely related to the optimal skin conditions, such as the rate of hydration, elasticity, the absence of wrinkles and expression lines, the ability to heal and regenerate.
Lithothamnium calcareum a red alga consisting of a robust thallus that forms thanks to the calcareous deposits present in the cell wall. These deposits are formed by minerals in highly bioavailable organic form, the red alga is a natural source of calcium, magnesium and silicon useful for bone health
Resveratrol. Collagen is degraded by proteolytic enzymes, called metalloproteinases. They break the long protein chains that make up collagen, forming shorter fragments with no mechanical properties. MMPs are a family of molecules similar in chemical structure, with different specificities for a wide variety of substrates, capable of degrading all the components of the extracellular matrix (collagen, elastin, laminins, proteoglycans). The consequence of this degenerative phenomenon is a general disorganization of the collagen fibers, which partially lose their supporting role, causing a partial atrophy of the extracellular matrix, which becomes soft and lacking in tone. Resveratrol reduces matrix-metalloprotease and act as inhibitor of metalloproteinases, resulting in proteolytic tissue damage or remodeling in pathophysiological conditions6. Blue Kollagen contains Polygonum cuspidatum extract, titrated in resveratrol, its roots have long been used in traditional Chinese and Japanese medicine and known for their many biological properties.
ANTI-AGING COMPONENTS to improve the condition of the skin in women and men
(Astaxanthin, Lycopene, Vitamin C, Resveratrol)
Astaxanthin is a lipid-soluble and red-orange oxycarotenoid pigment from microalgae7-9 with auspicious effects on human health. It protects organisms against a wide range of diseases with excellent safety and tolerability. Astaxanthin is a potent antioxidant and acts as a safeguard against oxidative damage through different mechanisms such as neutralizing of singlet oxygen, scavenging of radicals to prevent chain reactions, preservation of membrane structure through inhibition of lipid peroxidation, enhancement of immune system function.
Astaxanthin lipid solubility properties and accumulation in the skin after oral administration makes it beneficial to the skin8. Some researchers have shown that AST is a skin aging defense agent. It has been demonstrated that oral use of Astaxanthin might forestall the effects of UV-A radiation such as wrinkling9,10. Astaxanthin has been reported to improve the condition of the skin in women and men11. It can impede thickening of the skin and induce decrease in collagen against skin injury induced by UV-A12-14. Dietary Astaxanthin may improve barrier integrity and elasticity in photoaged human facial skin, and it is well tolerated15. It enervates the upregulation of MMP-1 and elastase of dermal fibroblasts of human, which are triggered by UV-A12
Lycopene is the natural coloring compound of the carotenoids that occur in plants and it is significant plant pigment not only due to its color but also it is well known for its health benefits.
Lycopene, has recently attracted considerable attention as a common dietary factor, consumption of which is associated with a decreased risk of major chronic diseases (cardiovascular disease, cancer) and antiaging effects16. One of the actively investigated beneficial effects of lycopene is its photoprotective action against UV‐induced damage to human skin17-19. Lycopene concentration in the skin correlates with its level in the plasma20, and accumulation of this carotenoid in the skin during dietary supplementation is well documented21-23
HAIR, NAIL SUPPORT
(Biotin, Zinc L-Cysteine)
Contains a selected combination of vitamins, minerals, amino acids to stimulate hair growth, restore hair structure, strengthen nails and maintain skin health, in synergy with the other components.
Zinc helps cell regeneration. Zinc is a trace element that is required by approximately 300 enzymes, contributing to growth, development, wound healing, immune function, and collagen synthesis, amongst many other functions24. It is essential, meaning that it cannot be synthesized by the body and must be obtained from the diet. Poor dietary intake of meat and fish can result in deficiency, especially when cereal grains that contain phytate, which chelates zinc and prevent absorption, are a dietary mainstay. Alopecia is often a presenting sign of zinc deficiency, along with a distinctive vesicobullous dermatosis, mucosal findings, and diarrhea. Progressive, diffuse, patchy nonscarring alopecia, hair dryness, and brittleness were reported in a 4-year-old girl who had deficient zinc levels.14 Her hair loss stopped 3 weeks after zinc supplementation, and she had no evidence of alopecia at a 4-month follow-up visit25.
Biotin is a cofactor of th e carboxylase group of enzymes. Hair regrowth was noticed within 1 month on biotin replacement. Some clinicians suggest biotin replacement for healthy patients with hair loss, possibly due to its beneficial effect on brittle nails and onychoschizia, A recent study from Switzerland demonstrated a 25 percent increase in nail plate thickness in patients with brittle nails who received biotin supplementation.26-28
L-cysteine is a conditionally essential sulphur amino acid, which is the building block of proteins. Besides contributing to many biological pathways, cysteine is a key component of the keratin protein by its ability to form disulfide bridges that confer strength and rigidity to the protein. Cysteine helps to build the keratin structure of hair and nails. Keratin is a fibrous protein that makes up the structure of skin, nails and hair. Without enough L-cysteine to maintain keratin structures, your hair will weaken and be prone to breakage. Hair consists of three layers, the cuticle, the cortex and the medulla. The cortex of hair contains keratin molecules bundled together into a fibrous structure that contains about 75% L-cysteine, which is what gives hair its strength29. Finally, L-cysteine is essential in helping the body to metabolize certain nutrients, including biotin.
- Improves the quality of the skin
- Reduce smoothing of wrinkles
- Maintain skin’s elasticity and firmness
- influence microcirculation that might cause beneficial effect in edema
- Reduces wrinkles hydrates the skin (of face and body)
- Promote collagen and elastine synteshis
- Slow collagen degradation
- Decrease in the degree of cellulite